Abstract

This aim of this research was to evaluate the antimicrobial activity of bile chemical substance from Northern Nigerian red goat (Capra hircus). The antimicrobial activity of the bile was done using standard methods on some selected microorganisms; Escherichia coli, staphylococcus aureus, Salmonella typhi, and Candida albicans. The result showed significant antimicrobial activity against the microorganisms with zone of inhibition ranging from 12 – 38 mm and Minimum inhibitory concentration (MIC) values ranging from 6.25 – 50 mg/ml. The MBC and MFC values against the selected microorganism range between 25 and 100 mg/ml. The study shows that the goat bile extract had significant antimicrobial activity and compare well with the standard drugs (Ciprofloxacin and Terbinefin) having the zone of inhibition in the range of 20 – 50 mm. Goat bile therefore has potentials to explore in the search for antibacterial or antifungal agent from nature.